Postdoctoral Research Associate

We are seeking a motivated and enthusiastic postdoctoral researcher with a background in chemical biology, biochemistry, molecular biology or a related discipline to contribute to an interdisciplinary project developing intracellular peptide screening technologies to investigate transcription factor function in mammalian cells.

Essential requirements:

A PhD (completed or nearing completion) in biochemistry, chemical biology, molecular biology, organic chemistry or a related discipline, or equivalent relevant research experience.

Practical laboratory experience in one or more of molecular biology, mammalian cell culture, peptide chemistry or protein biochemistry.

Experience in designing, conducting and troubleshooting experiments, with strong analytical and problem-solving skills.

An interest in protein–protein interactions, transcriptional regulation and the development of innovative molecular tools.

Ability to work independently, manage research activities effectively and contribute collaboratively to an interdisciplinary team.

Good written and verbal communication skills, including the ability to present research findings and contribute to scientific publications.

Desirable skills and experience:

Experience in mammalian cell culture, molecular cloning, transfection and the development of cell-based assays.

Experience in genetically encoded peptide libraries, intracellular screening or reporter-based selection systems.

Knowledge of peptide synthesis, peptide cyclisation, organic synthesis or chemical crosslinking.

Familiarity with biochemical or biophysical techniques such as circular dichroism, fluorescence polarisation or isothermal titration calorimetry.

Experience with luciferase reporter assays, Western blotting, RT-qPCR or related approaches to studying gene regulation.

We particularly welcome applicants who bring strong expertise in either molecular/cell biology or peptide chemistry and are interested in developing complementary skills. Full training and support will be available through our interdisciplinary research team.

This is a full time (36.5 hours per week) fixed term role with an expected duration of 12 months.

For an informal discussion regarding the role please contact Jody Mason at [email protected].

Benefits include: generous annual leave allowance with an additional 5 discretionary days; generous employer contributory pension schemes; cycle to work scheme; electric vehicle salary sacrifice scheme; staff discount at Team Bath gym; staff benefits including discounted postgraduate tuition and language courses; a wide range of personal and professional development opportunities such as apprenticeships and LinkedIn Learning; local discounts including free entry to the Holburne Museum in Bath; a family-friendly workplace; relocation allowance; visa reimbursement and interest-free loan to help with the cost of some immigration expenses; employee assistance services through Health Assured including access to the Wisdom app.

The University of Bath is committed to creating a health-supporting working environment where everyone can thrive. Support resources include staff support groups and networks, a network of Staff Wellbeing Champions, and a suite of tools and frameworks to enable staff to be at their best.